RVASSOC is a simple program for performing various tests for association between genotypes and disease status using biallelic sequence variants from unrelated cases and controls. It was designed to accommodate both rare variants and missing genotypes. More specifically, it implements the Cochran-Armitage (CA) max/sum tests, the Combined Multivariate and Collapsing (CMC) test, and the Weighted Sum Statistic (WSS) test for case-control designs with independent subjects, biallelic variants, and no covariates.
RVASSOC was written and is supported by:
Daniel D. Kinnamon
Division of Human Genetics
Department of Internal Medicine
The Ohio State University Wexner Medical Center
Biomedical Research Tower, Room 384
460 W. 12th Ave.
Columbus, OH 43210